Radamycin, a novel thiopeptide produced by streptomyces sp. RSP9. II. Physico-chemical properties and structure determination.

نویسندگان

  • Julián Castro Rodríguez
  • Gloria González Holgado
  • Ramón I Santamaría Sánchez
  • Librada M Cañedo
چکیده

The new cyclic peptide antibiotic, radamycin (1) and the known thiopeptide methylsulfomycin I (2) have been isolated from the fermentation broth of a Streptomyces sp. RSP9. The structure of radamycin was elucidated by NMR, LC-MS and FAB-MS and was established as a thiopeptide with oxazole and thiazole moieties, and several unusual amino acids.

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عنوان ژورنال:
  • The Journal of antibiotics

دوره 55 4  شماره 

صفحات  -

تاریخ انتشار 2002